Stream Bio launches LINKBRIGHT™ rapid conjugation kits through Sigma-Aldrich

Stream Bio, a UK-based company that develops and manufactures a range of innovative life science products, is pleased to announce the launch of its full range of Conjugated Polymer Nanoparticle (CPN™) LINKBRIGHT™ kits through MilliporeSigma, the U.S. and Canada life science business of Merck KGaA, Darmstadt, Germany, a leading science and technology company. The kits will be available worldwide under the Sigma-Aldrich product portfolio in the life science business. This will provide researchers around the world with easy access to the kits, allowing them to incorporate CPNs™ into their studies without the need for specialist chemistry capabilities.

Stream Bio’s CPNs are extremely bright fluorescent probes that have been successfully validated across many life science applications. These include microscopy, western blot, cell labelling, stem cell tracking, and in-vitro diagnostics, particularly lateral flow, where they have demonstrated remarkable sensitivity. CPNs have been shown to be up to 1000 times brighter than Qdots and other conventional fluorophores, providing exceptionally high sensitivity and imaging capabilities. In addition, CPNs provide stability across wide ranges of pH and temperature, allowing for repeat measurements months later if needed. These non-toxic probes are available in colours spanning the visible and near-infrared spectrum.

The full range of LINKBRIGHT kits covers the 16 different CPN emission wavelengths with two linkage chemistry options (amine and thiol). Antibodies and oligonucleotides can be rapidly conjugated in 30 minutes with only a few simple steps. The kits are available in 3 sizes depending on the amount of protein or oligo to be conjugated. Now, with the kits available through Sigma-Aldrich, they will be available to researchers around the globe.

 Andy Chaloner, CEO at Stream Bio, said: “This is an important step forward for Stream, making our innovative products accessible to the wider scientific community through the strong commercial network that Sigma-Aldrich can provide. Thanks to the fact our kits can accelerate time-consuming linkage processes and don’t require any specialist chemistry capabilities, we hope that many more researchers will be able to benefit from the unique properties of CPNs in their work.”

For further information about LINKBRIGHT kits, visit www.streambio.co.uk/linkbright-kits/ or purchase the kits via https://www.sigmaaldrich.com/GB/en/substance/conjugatedpolymernanoparticlecpn1234598765.