This event will be of interest to industrial chemists to discover what their contemporaries are working on in other companies and other areas of research, but also for academic chemists who want to find out the different challenges and focus that working in an industrial setting offers. It presents a superb opportunity for younger chemists to showcase their industrial research to an external audience. Prizes will be awarded for the best talk and runners-up. In addition, a lecture from a leading industrial chemist will conclude the proceedings. All talks will be followed by a chance to ask questions and the networking opportunity allows a possible exchange of ideas.

10:00

Registration and Refreshments

10:30

Introduction and Welcome

10:35

Discovery and development of selective CAMK1 inhibitors
Juliet Morgan, Sygnature Discovery

11:00

Aromatic Methylation as a Tool for Efficient Isotope Incorporation
Elliot Davenport, GSK

11:25

The value of kinetic modelling in the early stages of pharmaceutical development
Cristina Garcia-Morales, AstraZeneca

11:50

Lunch

13:15

Automating challenging chemistry in flow – The key to unlocking difficult to access libraries in medicinal chemistry
Daniel Maddox, Vernalis

13:40

AI-powered, patient-inspired drug enhancement and redevelopment for rare diseases
Rosemary Huckvale, Healx

14:05

Design of Chemical Probes for the Visualisation of the subcellular Localisation of inhaled PI3Kδ inhibitors using Biorthogonal Chemistry and NanoSIMS Imaging Strategies
Maxime Rouah, GSK

14:30

Refreshment break

15:00

PROTAC-kling permeability and cell selectivity issues using an antibody-mediated approach
Karina Chan, GSK

15:25

Discovery of AZD4625, a covalent allosteric inhibitor of the mutant GTPase KRAS
Doyle Cassar, AstraZeneca

15:50

Plenary Talk – Reflections of an old(er) chemist in industry…
Allan Jordan, VP of Oncology Drug Discovery, Sygnature Discovery

16:35

Prize giving

16:45

Networking Reception